Look up proteins

uniprot.search_proteins

FreeLive now

Search UniProtKB by name, gene, organism or accession (e.g. "insulin human", "BRCA1", "P69905") and get protein name, genes, organism, length and curated function.

Inputs

Name	Type	Description
`query`required	string	Search text or a UniProt accession
`reviewed_only`	boolean	Only manually reviewed (Swiss-Prot) entriesdefault: true
`limit`	integer	default: 5; range: 1 to 10

Example output

{"query":{"query":"hemoglobin human","reviewed_only":true},"count":3,"proteins":[{"accession":"P68871","entry_name":"HBB_HUMAN","protein":"Hemoglobin subunit beta","genes":["HBB"],"organism":"Homo sapiens","taxon_id":9606,"length_aa":147,"reviewed":true,"function":"Involved in oxygen transport from the lung to the various peripheral tissues","page":"https://www.uniprot.org/uniprotkb/P68871/entry"},{"accession":"P02042","entry_name":"HBD_HUMAN","protein":"Hemoglobin subunit delta","genes":["HBD"],"organism":"Homo sapiens","taxon_id":9606,"length_aa":147,"reviewed":true,"function":"Involved i...

Data license

CC BY 4.0 · Data from UniProt (The UniProt Consortium), CC BY 4.0. Source

Try it

…

Call it

{
  "jsonrpc": "2.0",
  "id": 1,
  "method": "tools/call",
  "params": {
    "name": "uniprot.search_proteins",
    "arguments": {
      "query": "hemoglobin human",
      "limit": 3
    }
  }
}

curl -sS -X POST https://www.realworldmcp.com/api/call/uniprot.search_proteins \
  -H 'content-type: application/json' \
  -d '{"query": "hemoglobin human", "limit": 3}'

const res = await fetch("https://www.realworldmcp.com/api/call/uniprot.search_proteins", {
  method: "POST",
  headers: { "content-type": "application/json" },
  body: JSON.stringify({"query": "hemoglobin human", "limit": 3})
});
console.log(await res.json());